- Alan Beckwith - actor/aerospace engineer
- Alexander Haig, secretary of state
- Andrew Mellon, financier
- Andrew Wyeth, painter
- Anthony Wayne, general
- Arnold Palmer, golfer
- Andrew Carnegie, industrialist/philanthropist
- Betsy Griscom Ross, flag maker
- Bill Cosby, actor
- Charles Goodyear, inventor
- Daniel Boone, frontiersman
- Dick Clark, television pioneer
- Dr. Benjamin Rush, father of American Psychiatry
- Dr. Jonas Salk, founder of the Polio Vaccine
- Dwight David Eisenhower, general, President
- Edward Goodrich Acheson, inventor
- Ethel Waters, singer and actress
- Gelsey Kirkland, ballerina
- Gene Kelly, dancer and actor
- General George G. Meade, Civil War general
- George C. Marshall, five-star general
- George Catlin, Indian expert, poet
- George McClellan, general
- George R. Stibitz, inventor
- Gertrude Stein, author
- Gifford Pinchot, conservationist
- Grace Kelly, actress, Princess of Monaco
- Henry Clay Frick, industrialist
- Henry J. Heinz, industrialist
- Henry Harley "hap" Arnold, Air Force hero
- Henry Steele Commager, historian
- Hezekiah Niles, journalist
- James Buchanan, U.S. president
- James Stewart, actor
- Jeff Lynn Goldblum, actor
- Jim Thorpe, athlete
- Jimmy Dorsey, band leader
- Jimmy Stewart, actor
- Joe Montana, athlete
- Joe Namath, athlete
- Joe Paterno, football coach
- John Barrymore, actor
- John Fulton Reynolds, Civil War general
- John Updike, author
- Julius Erving, basketball player
- Julius Sturgis, pretzel baker
- Lee Iacocca, auto executive
- Louisa May Alcott, novelist
- Lucretia Mott, anti-slavery and Women's Rights Leader
- Marian Anderson, contralto
- Mario Lanza, actor and singer
- Martha Graham, choreographer
- Michael Keaton, actor
- Milton Hershey, philanthropist, businessman
- Molly Pitcher, Revolutionary War heroine
- Perry Como, singer
- Pearl Buck, author
- Reggie Jackson, baseball player
- Robert E. Peary, explorer
- Robert Fulton, inventor
- Robinson Jeffers, poet
- S. S. Kresge, merchant
- Samuel Barber, composer
- Stephanie Louise Kwolek, inventor
- Stephen Foster, composer
- Stephen Vincent Benet, poet, author
- Tom Mix, actor
- Tommy Dorsey, bandleader
- W. C. Fields, comedian
- Wallis Warfield, Duchess of Windsor
- Walter E. Diemer, inventor
- William Edward Hanford, inventor
- William Penn, founder of Pennsylvania
- Winfield Scott Hancock, Civil War general
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